Mission

Our mission is to pioneer innovative approaches for stabilizing vulnerable atherosclerotic plaques in carotid arteries and halting the progression of AAA disease. Through comprehensive research utilizing human biobank materials, preclinical models, and cutting-edge organoid systems, we aim to elucidate the molecular mechanisms and genetic factors governing the fate of vascular smooth muscle cells within fibrous caps of advanced lesions. Our focus extends to understanding the roles of non-coding RNAs, including microRNAs, long non-coding RNAs, and circular RNAs, in cardiovascular homeostasis and disease development. By developing novel models and treatment strategies, we strive to translate our findings into effective therapeutic interventions that improve patient outcomes and reduce the burden of cardiovascular disease.

Vision

• Become a global leader in cardiovascular research, recognized for pioneering approaches to understanding vascular diseases.
• Foster interdisciplinary collaborations to advance knowledge of molecular mechanisms underlying atherosclerotic plaques and AAA disease.
• Lead the development of personalized therapeutic interventions such as multi-omics data tailored to target non-coding RNAs and other key molecular regulators.
• Transform the landscape of cardiovascular medicine by translating innovative research findings into effective clinical treatments.